BDBM50227193 CHEBI:17712::Xanthine

SMILES O=c1[nH]c2[nH]cnc2c(=O)[nH]1

InChI Key InChIKey=LRFVTYWOQMYALW-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50227193   

TargetAcetylcholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50227193(CHEBI:17712 | Xanthine)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate treated 5 mins before substrate addition measured up to 4 mins by Ellman's metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Waterloo

Curated by ChEMBL
LigandPNGBDBM50227193(CHEBI:17712 | Xanthine)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human BuChE using S-butyrylthiocholine iodide as substrate treated 5 mins before substrate addition measured up to 4 mins by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a/A2b(Rat)
Merrell Dow Research Institute

Curated by ChEMBL
LigandPNGBDBM50227193(CHEBI:17712 | Xanthine)
Affinity DataKi:  1.30E+5nMAssay Description:Inhibition of adenosine stimulated accumulation of cyclic AMP at Adenosine A2 receptor of VA13 fibroblasts of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed