BDBM50468263 Sepantronium Bromide::YM 155::YM-155

SMILES COCC[n+]1c(C)n(Cc2cnccn2)c2c1C(=O)c1ccccc1C2=O

InChI Key InChIKey=OTSOOHRUMBRSHZ-UHFFFAOYSA-N

Data  4 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50468263   

TargetSerine/threonine-protein kinase PAK 1(Human)
Pak Research Center

Curated by ChEMBL
LigandPNGBDBM50468263(Sepantronium Bromide | YM 155 | YM-155)
Affinity DataIC50: 500nMAssay Description:Inhibition of PAK1 in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The State University of New Jersey

Curated by ChEMBL
LigandPNGBDBM50468263(Sepantronium Bromide | YM 155 | YM-155)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of full-length SARS-CoV-2 papain-like protease (1564 to 1878 residues) expressed in Escherichia coli Rosetta (DE3) using Arg-Leu-Arg-Gly-G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details Article
PubMed
TargetInterleukin enhancer-binding factor 3(Homo sapiens)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50468263(Sepantronium Bromide | YM 155 | YM-155)
Affinity DataKd:  5.70nMAssay Description:Binding affinity to ILF3 (unknown origin) assessed as dissociation constant at upto 1 uM by SPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetTranscription factor Sp1(Human)
University of Toledo College of Medicine and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50468263(Sepantronium Bromide | YM 155 | YM-155)
Affinity DataIC50: 8nMAssay Description:Inhibition of human SP1 transfected in PC-3 cells by renilla luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
University of Toledo College of Medicine and Life Sciences

Curated by ChEMBL
LigandPNGBDBM50468263(Sepantronium Bromide | YM 155 | YM-155)
Affinity DataIC50: 2nMAssay Description:Inhibition of human RIPK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed