BDBM50662256 Desidustat::ZYAN1::Zyan-1

SMILES O=C(O)CNC(=O)c1c(O)c2ccccc2n(OCC2CC2)c1=O

InChI Key InChIKey=IKRKQQLJYBAPQT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50662256   

TargetGamma-butyrobetaine dioxygenase(Human)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662256BDBM50662256(Desidustat | Zyan-1 | ZYAN1)
Affinity DataIC50: 420nMAssay Description:Inhibition of full-length recombinant human BBOX using GBB/2-OG as substrate preincubated for 15 mins followed by substrate addition measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662256BDBM50662256(Desidustat | Zyan-1 | ZYAN1)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetAspartyl/asparaginyl beta-hydroxylase(Human)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662256BDBM50662256(Desidustat | Zyan-1 | ZYAN1)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of AspH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetBifunctional peptidase and arginyl-hydroxylase JMJD5(Homo sapiens)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662256BDBM50662256(Desidustat | Zyan-1 | ZYAN1)
Affinity DataIC50: 4.83E+4nMAssay Description:Inhibition of JMJD5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
University of Oxford

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50662256BDBM50662256(Desidustat | Zyan-1 | ZYAN1)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of KDM4A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed