BDBM50253622 2-[4-(4-chlorophenyl)-5-p-tolyl-4H-[1,2,4]triazol-3-ylsulfanyl]-1-(3,4-dihydroxyphenyl)ethanone::CHEMBL459929::cid_1383304

SMILES Cc1ccc(cc1)-c1nnc(SCC(=O)c2ccc(O)c(O)c2)n1-c1ccc(Cl)cc1

InChI Key InChIKey=VNJJARMKEXNMBM-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50253622   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50253622(cid_1383304 | CHEMBL459929 | 2-[4-(4-chlorophenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetAlkaline phosphatase, germ cell type(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50253622(cid_1383304 | CHEMBL459929 | 2-[4-(4-chlorophenyl)...)
Affinity DataIC50: 1.53E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2011
Entry Details
PCBioAssay
TargetM-phase inducer phosphatase 1(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(cid_1383304 | CHEMBL459929 | 2-[4-(4-chlorophenyl)...)
Affinity DataIC50: 820nMAssay Description:Inhibition of Cdc25A (336-523) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(cid_1383304 | CHEMBL459929 | 2-[4-(4-chlorophenyl)...)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of Cdc25B (378-566) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(cid_1383304 | CHEMBL459929 | 2-[4-(4-chlorophenyl)...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human Cdc25AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(cid_1383304 | CHEMBL459929 | 2-[4-(4-chlorophenyl)...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human Cdc25BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50253622(cid_1383304 | CHEMBL459929 | 2-[4-(4-chlorophenyl)...)
Affinity DataKi:  3.75E+4nMAssay Description:Binding affinity to Cdc25A (336-523) expressed in Escherichia coli by steady-state kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed