BDBM50244718 CHEMBL460273::JNJ-1661010::N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide::cid_2809273

SMILES O=C(Nc1ccccc1)N1CCN(CC1)c1nc(ns1)-c1ccccc1

InChI Key InChIKey=BHBOSTKQCZEAJM-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50244718   

TargetUbiquitin-conjugating enzyme E2 N(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM50244718(cid_2809273 | CHEMBL460273 | JNJ-1661010 | N-pheny...)
Affinity DataIC50: 2.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50244718(cid_2809273 | CHEMBL460273 | JNJ-1661010 | N-pheny...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human FAAH preincubated for 40 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50244718(cid_2809273 | CHEMBL460273 | JNJ-1661010 | N-pheny...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human FAAH preincubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50244718(cid_2809273 | CHEMBL460273 | JNJ-1661010 | N-pheny...)
Affinity DataIC50: 34nMAssay Description:Inhibition of rat FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50244718(cid_2809273 | CHEMBL460273 | JNJ-1661010 | N-pheny...)
Affinity DataIC50: 33nMAssay Description:Inhibition of human FAAH preincubated for 20 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50244718(cid_2809273 | CHEMBL460273 | JNJ-1661010 | N-pheny...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human FAAH after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50244718(cid_2809273 | CHEMBL460273 | JNJ-1661010 | N-pheny...)
Affinity DataIC50: 33nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50244718(cid_2809273 | CHEMBL460273 | JNJ-1661010 | N-pheny...)
Affinity DataIC50: 10nMAssay Description:Inhibition of rat FAAH assessed as hydrolysis of anandamido-amino-methyl-cumarinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50244718(cid_2809273 | CHEMBL460273 | JNJ-1661010 | N-pheny...)
Affinity DataIC50: 33nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50244718(cid_2809273 | CHEMBL460273 | JNJ-1661010 | N-pheny...)
Affinity DataIC50: 34nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50244718(cid_2809273 | CHEMBL460273 | JNJ-1661010 | N-pheny...)
Affinity DataIC50: 11nMAssay Description:Apparent inhibition of human FAAH expressed in CHO-K1 cells using ethanolamine 1-3[H] as substrate after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed