BDBM50258233 6-bromo-4-(4-ethylpiperazin-1-yl)quinazoline::CHEMBL494838::cid_720660

SMILES CCN1CCN(CC1)c1ncnc2ccc(Br)cc12

InChI Key InChIKey=QRIYSXNSZBAVNJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50258233   

TargetHuntingtin(Human)
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50258233(CHEMBL494838 | cid_720660 | 6-bromo-4-(4-ethylpipe...)
Affinity DataIC50: 2.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetHuntingtin(Human)
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50258233(CHEMBL494838 | cid_720660 | 6-bromo-4-(4-ethylpipe...)
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of Huntingtin protein aggregation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed