BDBM50242284 CHEMBL487805::scutellarin

SMILES O[C@H]1[C@H](Oc2cc3oc(cc(=O)c3c(O)c2O)-c2ccc(O)cc2)O[C@@H]([C@@H](O)[C@@H]1O)C(O)=O

InChI Key InChIKey=DJSISFGPUUYILV-UHFFFAOYSA-N

Data  3 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50242284   

Target5-hydroxytryptamine receptor 7(Human)
Tom'S of Maine

Curated by ChEMBL
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataIC50: 6.34E+4nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetATP-binding cassette sub-family C member 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of human MRP2-mediated estradiol-17beta-D-glucuronide formation using inside-out membrane vesicles by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BCRP-mediated methotrexate transport using inside-out membrane vesicles by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataIC50: 5.06E+4nMAssay Description:Inhibition of Influenza A PR/8/34 H1N1 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataIC50: 4.73E+4nMAssay Description:Inhibition of Influenza A Jinan/15/90 H3N2 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetNeuraminidase(Influenza A virus)
Peking Union Medical College

Curated by ChEMBL
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataIC50: 5.99E+4nMAssay Description:Inhibition of Influenza A Jiangsu/10/2003 virus neuraminidase activity by MUN-ANA substrate based fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataIC50: 1.92E+4nMAssay Description:Inhibition of METTL3/METTL14 (unknown origin) using RNA 5'-GGACUGGACUGGACU-3' as substrate incubated for 2 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of human recombinant P-gp ATPase activity in isolated membranes incubated in presence of verapamil by firefly luciferase based luminescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataIC50: 1.99E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataIC50: 1.99E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSolute carrier organic anion transporter family member 2B1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataKi:  2.59E+4nMAssay Description:Drug uptake assessed as OATP2B1 (unknown origin)-mediated drug transport expressed in HEK293 cells after 7 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataKi:  9.66E+4nMAssay Description:Drug metabolism assessed as human recombinant UGT1A1-mediated formation of scutellarein-6,7-diglucuronide after 25 mins by HPLC/UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 1A10(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50242284(scutellarin | CHEMBL487805)
Affinity DataKi:  2.08E+5nMAssay Description:Drug metabolism assessed as human recombinant UGT1A10-mediated formation of scutellarein-6,7-diglucuronide after 25 mins by HPLC/UV analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/8/2016
Entry Details Article
PubMed