BDBM152699 (S)-2-Amino-5-propionimidamidopentanoic acid (8)::hDDAH inhibitor, 1d

SMILES CCC(=N)NCCC[C@H](N)C(O)=O

InChI Key InChIKey=ZYIBCZWVLDODOL-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 152699   

TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

LigandPNGBDBM152699((S)-2-Amino-5-propionimidamidopentanoic acid (8) |...)
Affinity DataKi:  7.25E+3nM IC50: 1.61E+4nMpH: 7.4Assay Description:The assay mixture contained L-arginine (10 μM), NADPH (100 μM), oxyhemoglobin (0.125 mg/mL), tetrahydrobiopterin (10 μM), and differen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2015
Entry Details Article
PubMed
TargetN(G),N(G)-dimethylarginine dimethylaminohydrolase 1(Human)
Christian-Albrechts-University

LigandPNGBDBM152699((S)-2-Amino-5-propionimidamidopentanoic acid (8) |...)
Affinity DataKi:  1.45E+5nM ΔG°:  -5.44kcal/molepH: 7.4 T: 2°CAssay Description:A colorimetric assay was carried out in 150 μL 50 mM potassium phosphate buffer pH 7.4 containing 4 μg of recombinant hDDAH-1 and varying c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed