BDBM15410 N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)phenyl]thiophene-2-sulfonamide::naphthol compound 13

SMILES Oc1ccc(NS(=O)(=O)c2cccs2)cc1-c1c(O)ccc2ccccc12

InChI Key InChIKey=NYXDSXZBPWSAFA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15410   

TargetHeat shock protein HSP 90-beta(Human)
Vernalis (R&D)

LigandPNGBDBM15410(N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)phenyl]th...)
Affinity DataIC50: 600nMpH: 7.4 T: 2°CAssay Description:The assay is based upon displacement of a fluorescently labeled molecule, which binds specifically to the ATP-binding site of full-length human Hsp90...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed