BDBM15669 N-(5-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide::Pyrrolidine Carboxamide Compound d3

SMILES Cc1ccc(cc1NC(=O)[C@H]2CC(=O)N(C2)C3CCCCC3)Cl

InChI Key InChIKey=RJWMDETWDDESBP-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15669   

TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of California San Francisco

LigandPNGBDBM15669(N-(5-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrr...)
Affinity DataIC50: 970nMAssay Description:The assay measured the NADH-dependent catalysis of an octenoyl-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of California San Francisco

LigandPNGBDBM15669(N-(5-chloro-2-methylphenyl)-1-cyclohexyl-5-oxopyrr...)
Affinity DataIC50: 970nMAssay Description:Inhibition of Mycobacterium tuberculosis InhA using 2-trans-dodecenoyl-CoA as substrate by fluorimetric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)