BDBM177937 US9120797, 35

SMILES CC1Cc2c([nH]c3ccc(F)cc23)C2(CCC(CC2)(N(C)C)c2ccccc2)O1

InChI Key InChIKey=PFZLXGIYSYVVJF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 177937   

TargetMu-type opioid receptor(Human)
Gruenenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 177937BDBM177937(US9120797, 35)
Affinity DataKi:  61nM ΔG°:  -9.84kcal/moleT: 2°CAssay Description:The receptor affinity for the human mu-opiate receptor was determined in a homogeneous batch in microtitre plates. For this, dilution series of the p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent

TargetOpioid growth factor receptor-like protein 1(Human)
Gruenenthal

US Patent
LigandChemical structure of BindingDB Monomer ID 177937BDBM177937(US9120797, 35)
Affinity DataKi:  83nM ΔG°:  -9.65kcal/molepH: 7.4 T: 2°CAssay Description:The cyclohexane derivatives of the general formula I were investigated in a receptor binding assay with 3H-nociceptin/orphanin FQ with membranes from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details
US Patent