BDBM191574 6-(3-bromophenyl)pteridine-2,4,7-triamine (18)

SMILES Nc1nc(N)c2nc(c(N)nc2n1)-c1cccc(Br)c1

InChI Key InChIKey=UWFFWZGQGRBIBG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 191574   

TargetCasein kinase I isoform alpha(Human)
Max Planck Institute of Molecular Physiology

LigandPNGBDBM191574(6-(3-bromophenyl)pteridine-2,4,7-triamine (18))
Affinity DataIC50: 9.30E+3nMAssay Description:Single-point measurements analyses and subsequent dose-dependent investigations of selected pteridine derivatives for inhibition of CK1α were pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2016
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Max Planck Institute of Molecular Physiology

LigandPNGBDBM191574(6-(3-bromophenyl)pteridine-2,4,7-triamine (18))
Affinity DataIC50: 2.50E+3nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2016
Entry Details Article
PubMed