BDBM210834 US9290467, 4

SMILES c1ccc2c(c1)C(=O)N[C@@H](Cc3ccc(c(c3)Cl)OC/C=C/CO2)C(=O)NC4(CC4)C#N

InChI Key InChIKey=DAGMBGOOMHAGIF-UHFFFAOYSA-N

Data  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 210834   

TargetProcathepsin L(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM210834(US9290467, 4)
Affinity DataIC50: 13.8nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2017
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)