BDBM221071 SPHINX scaffold, 1

SMILES Cc1ccc(o1)C(=O)Nc2cc(ccc2N3CCN(CC3)C)C(F)(F)F

InChI Key InChIKey=STWLHUZLPCVTAS-UHFFFAOYSA-N

Data  1 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221071   

TargetSRSF protein kinase 1(Human)
Exonate

LigandPNGBDBM221071(SPHINX scaffold, 1)
Affinity DataIC50: 31nMpH: 7.5 T: 2°CAssay Description:A reaction buffer containing 200 mM Tris pH 7.5, 100 mM MgCl2 and 0.1 mg/ml BSA was added to 43 μM SRSF1Arg-Ser (RS) peptide (NH2-RSPSYGRSRSRSRS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)