BDBM28662 2-[4-(3-{[2-(2-chloro-6-fluorophenyl)ethyl][(2,3-dichlorophenyl)carbamoyl]amino}propyl)phenoxy]-2-methylpropanoic acid::CHEMBL435278::[3H]GW 2433

SMILES CC(C)(C(=O)O)Oc1ccc(cc1)CCCN(CCc2c(cccc2Cl)F)C(=O)Nc3cccc(c3Cl)Cl

InChI Key InChIKey=YMWJDWJXIXITMD-UHFFFAOYSA-N

Data  6 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 28662   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM28662(CHEMBL435278 | 2-[4-(3-{[2-(2-chloro-6-fluoropheny...)
Affinity DataEC50:  170nMAssay Description:Agonist activity for Human PPAR alpha receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM28662(CHEMBL435278 | 2-[4-(3-{[2-(2-chloro-6-fluoropheny...)
Affinity DataEC50:  270nMAssay Description:Agonist activity for murine PPAR alpha receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Mouse)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM28662(CHEMBL435278 | 2-[4-(3-{[2-(2-chloro-6-fluoropheny...)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity for murine PPAR gamma receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM28662(CHEMBL435278 | 2-[4-(3-{[2-(2-chloro-6-fluoropheny...)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity for Human PPAR gamma receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM28662(CHEMBL435278 | 2-[4-(3-{[2-(2-chloro-6-fluoropheny...)
Affinity DataEC50:  190nMAssay Description:Agonist activity for Human PPAR delta receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Mouse)
Glaxo Wellcome Research & Development

Curated by ChEMBL
LigandPNGBDBM28662(CHEMBL435278 | 2-[4-(3-{[2-(2-chloro-6-fluoropheny...)
Affinity DataEC50:  410nMAssay Description:Agonist activity for murine PPAR delta receptor in transcriptional activation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)