BDBM299398 N-[3-(4-amino- quinazolin-6-yl)- 5-fluoro-phenyl]- 2-pyrrolidin-1- yl-acetamide::US9592235, Example 191::US9855269, Compound 37

SMILES Nc1ncnc2ccc(cc12)-c1cc(F)cc(NC(=O)CN2CCCC2)c1

InChI Key InChIKey=GDCGMGVDMXRLGC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299398   

LigandPNGBDBM299398(US9592235, Example 191 | N-[3-(4-amino- quinazolin...)
Affinity DataIC50: 58.6nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
Go to US Patent

LigandPNGBDBM299398(US9592235, Example 191 | N-[3-(4-amino- quinazolin...)
Affinity DataIC50: 58.6nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
Go to US Patent