BDBM50012798 (E)-2,6-dimethyl-4-styrylphenol::2,6-Dimethyl-4-styryl-phenol::2,6-dimethyl-4-[(E)-2-phenylethenyl]phenol::2,6-dimethyl-4-styrylphenol::CHEMBL55960

SMILES Cc1cc(cc(c1O)C)\C=C\c2ccccc2

InChI Key InChIKey=PAHKYLUYTGBFNW-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50012798   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012798((E)-2,6-dimethyl-4-styrylphenol | 2,6-dimethyl-4-s...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human neutrophil 5-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransthyretin(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50012798((E)-2,6-dimethyl-4-styrylphenol | 2,6-dimethyl-4-s...)
Affinity DataIC50: 3.08E+3nMpH: 4.4Assay Description:Inhibition of wild type TTR amyloidogenesis assessed as inhibition of fibril formation after 72 hrs at pH 4.4 by spectrophotometry relative to untrea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1/2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50012798((E)-2,6-dimethyl-4-styrylphenol | 2,6-dimethyl-4-s...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human platelet Prostaglandin G/H synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed