BDBM50017550 CHEMBL76399::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine::N*6*-Propyl-4,5,6,7-tetrahydro-benzothiazole-2,6-diamine (Pramipexole, PPX)::Pramipexole

SMILES CCCNC1CCc2nc(N)sc2C1

InChI Key InChIKey=FASDKYOPVNHBLU-UHFFFAOYSA-N

Data  23 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 50017550   

TargetD(2) dopamine receptor(Bovine)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against Dopamine receptor D2 in calf corpus striatum using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataIC50: 280nMAssay Description:Inhibitory activity against Dopamine receptor D2 in rat corpus striatum using [3H]Apomorphine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi:  10nMAssay Description:Tested for the ability to displace [125I]iodosulpiride from human cloned Dopamine receptor D3, expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2018
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi:  10.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi:  129nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi:  631nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi:  692nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi:  955nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi:  1.66E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi:  1.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi:  1.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465](Rat)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi:  5.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi:  8.32E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50017550(Pramipexole | CHEMBL76399 | N*6*-Propyl-4,5,6,7-te...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed