BDBM50019066 CHEMBL3288147

SMILES c1ccc(c(c1)CC(=O)N2CCN(CC2)c3c4c5c(sc4ncn3)CCC5)C(F)(F)F

InChI Key InChIKey=XMIMIFRXLOGETC-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50019066   

TargetRetinol-binding protein 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50019066(CHEMBL3288147)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant RBP4-transthyretin interaction by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRetinol-binding protein 4(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50019066(CHEMBL3288147)
Affinity DataIC50: 280nMAssay Description:Displacement of [3H]-retinol from human recombinant RBP4 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)