BDBM50025048 CHEMBL3355099

SMILES c1ccc(cc1)CC[C@H](N)P(=O)(O)O

InChI Key InChIKey=NAPHUBPIUWHFCT-UHFFFAOYSA-N

Data  5 KI

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50025048   

TargetAminopeptidase N(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50025048(CHEMBL3355099)
Affinity DataKi:  230nMAssay Description:Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50025048(CHEMBL3355099)
Affinity DataKi:  4.08E+3nMAssay Description:Inhibition of pig recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetCytosol aminopeptidase [33-68,L62W](Pig)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50025048(CHEMBL3355099)
Affinity DataKi:  5.03E+3nMAssay Description:Inhibition of pig recombinant leucine aminopeptidase after 30 to 60 mins by morrison's equationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2016
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50025048(CHEMBL3355099)
Affinity DataKi:  5.55E+3nMAssay Description:Inhibition of recombinant human ERAP1 using L-AMC as substrate measured for 15 to 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum aminopeptidase 2(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50025048(CHEMBL3355099)
Affinity DataKi:  4.70E+4nMAssay Description:Inhibition of human ERAP2 preincubated for 30 to 60 mins followed by addition of Arg-AMC as substrate measured for 15 mins by spectrofluorimetric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)