BDBM50025206 (6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)-dimethyl-ammonium::TL99

SMILES C[NH+](C)C1CCc2cc(O)c(O)cc2C1

InChI Key InChIKey=JWLJBTDXCBIGBW-UHFFFAOYSA-O

Data  31 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 32 hits for monomerid = 50025206   

TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKd:  4.60E+3nMAssay Description:Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/3/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  0.910nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Rat)
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  1.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2012
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  2.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2011
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
Janssen Research Foundation

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  2.51nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  6.03nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  7.22nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
U. 109

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2011
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  41.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor [16-465](Rat)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  46.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  52.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  57nMAssay Description:Compound was tested for binding affinity against dDopamine receptor D1 using [3H]fenoldopam as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  57.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  66nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2011
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  67.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  77.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  255nMAssay Description:Compound was tested for inhibition of [3H]spiroperidol binding against Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  340nMAssay Description:Affinity towards Dopamine receptor D2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  776nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  1.95E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  2.04E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  2.29E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  2.34E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  2.69E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  3.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Human)
Va Medical Center

Curated by ChEMBL
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi:  5.40E+3nMAssay Description:Affinity towards Dopamine receptor D1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Institut De Recherches Servier

Curated by PDSP Ki Database
LigandPNGBDBM50025206((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/13/2012
Entry Details Article
PubMed