BDBM50030791 CHEMBL3342402

SMILES Cc1ccc(cc1)-c1csc2nnc(SCC(=O)Nc3ccc4OCOc4c3)n12

InChI Key InChIKey=XYXNYQAJSYUYNZ-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50030791   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human IDO1 assessed as reduction in convertion of N-formylkynurenine to kynurenine incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human IDO2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2016
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human IDO1 by Bridge-IT Tryptophan fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 2(Human)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human IDO2 using Trp as substrate after 90 mins by Bridge-IT tryptophan fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Colorado College

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)
Affinity DataIC50: 6.25E+4nMAssay Description:Inhibition of human TDO using Trp as substrate after 90 mins by Bridge-IT tryptophan fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human IDO1 using Trp as substrate after 90 mins by Bridge-IT tryptophan fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of N-terminal 6His-tagged human recombinant IDO1 expressed in Escherichia coli BL21 using tryptophan as substrate after 90 mins by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human IDO1 incubated for 60 mins in presence of L-tryptophan by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Dainippon Sumitomo Pharma

Curated by ChEMBL
LigandPNGBDBM50030791(CHEMBL3342402)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human N-terminal his6-tagged IDO1 expressed in Escherichia coli BL21 using L-tryptophan as substrate incubated for 90 mins by methylene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed