BDBM50031747 CHEMBL3360318

SMILES COc1ccc(cc1)-c1cccc2nc(NC(=O)C3CC3)nn12

InChI Key InChIKey=PFUHEDXCYMUYNJ-UHFFFAOYSA-N

Data  17 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50031747   

TargetMitogen-activated protein kinase 14(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant JAK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase TBK1(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of TBK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of RIPK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetProtein-tyrosine kinase 2-beta(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 3.18E+3nMAssay Description:Inhibition of PYK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 138nMAssay Description:Inhibition of human recombinant JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 5(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAPKAPK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 4.44E+3nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of IKKbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 7.11E+3nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 5.74E+3nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 519nMAssay Description:Inhibition of human recombinant TYK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50031747(CHEMBL3360318)
Affinity DataIC50: 528nMAssay Description:Inhibition of human recombinant JAK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed