BDBM50034993 (S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-imidazol-1-yl)-butyl]-phenyl}-acetylamino)-propionylamino]-hexanoic acid (2-cyclohexyl-ethyl)-amide::CHEMBL6269::SC-58272::[CYCLOHEXYLETHYL]-[[[[4-[2-METHYL-1-IMIDAZOLYL-BUTYL]PHENYL]ACETYL]-SERYL]-LYSINYL]-AMINE

SMILES Cc1nccn1CCCCc1ccc(CC(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC2CCCCC2)cc1

InChI Key InChIKey=WHLPIOSHBKQGHA-UHFFFAOYSA-N

Data  2 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50034993   

LigandPNGBDBM50034993((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)
Affinity DataIC50: 60nMAssay Description:Compound was tested for its inhibitory activity against Candida albicans N-Myristoyltransferase (NMT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50034993((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)
Affinity DataIC50: 830nMAssay Description:Inhibitory activity against Candida albicans N-myristoyltransferase (CaNmt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2018
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50034993((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)
Affinity DataIC50: 1.40E+5nMAssay Description:Inhibitory activity against human N-myristoyltransferase (HsNmt)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2018
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Baker's yeast)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50034993((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)
Affinity DataIC50: 24nMAssay Description:Inhibition of Saccharomyces cerevisiae NMTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50034993((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)
Affinity DataIC50: 1.41E+4nMAssay Description:Tested for Inhibitory concentration against human N-myristoyltransferase (NMT) in radiochemical HPLC end point assay with peptide GNAASARR-NH2 and [3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2018
Entry Details

TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50034993((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)
Affinity DataIC50: 56nMAssay Description:Inhibition of Candida albicans N-myristoyltransferase (NMT) with peptide GNAASARR-NH2 and [3H]myristoyl-CoA at 1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2018
Entry Details

TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50034993((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)
Affinity DataIC50: 56nMAssay Description:Inhibition activity against N-myristoyltransferase (NMT) of candida albicans.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50034993((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition activity against N-myristoyltransferase (NMT) of human.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50034993((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibitory activity against human N-Myristoyltransferase (NMT).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50034993((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)
Affinity DataIC50: 56nMAssay Description:Inhibitory activity against Candida albicans N-Myristoyltransferase (NMT).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase(Yeast)
G.D. Searle And

Curated by ChEMBL
LigandPNGBDBM50034993((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)
Affinity DataKi:  31nMAssay Description:The Compound was tested for the inhibition potency against Candida albicans N-myristoyltransferase (NMT) and reported as apparent KiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlycylpeptide N-tetradecanoyltransferase 1/2(Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50034993((S)-6-Amino-2-[(S)-3-hydroxy-2-(2-{4-[4-(2-methyl-...)
Affinity DataKi:  31nMAssay Description:Apparent binding affinity against Candida albicans N-Myristoyltransferase (NMT).More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed