BDBM50035710 CHEMBL3359893

SMILES CN1CCN(CC1)c1ccc(cc1)-c1cnc2[nH]c3cnc(cc3c2c1)C(O)=O

InChI Key InChIKey=AVGXCPYDUVBUKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50035710   

TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035710(CHEMBL3359893)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ChK1 in human HT-29 cells assessed as phospho-histone H3 by Isobologram assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50035710(CHEMBL3359893)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of recombinant ChK1 (unknown origin) using AKT substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details Article
PubMed