BDBM50039974 CHEMBL3358341

SMILES CC(C)(C#N)c1cc2c(c(c1)F)C(=O)N(CC2)c3cccc(c3CO)C4=CN(C(=O)C(=C4)Nc5ccc(cn5)N6CCN(CC6)C)C

InChI Key InChIKey=AGMLIXLHTZGRPZ-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50039974   

TargetTyrosine-protein kinase BTK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50039974(CHEMBL3358341)
Affinity DataIC50: 50nMAssay Description:Inhibition of BTK in human whole blood assessed as decrease in CD69 positive cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/17/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)