BDBM50078154 CHEMBL3417694

SMILES Cc1ccccc1c2cccc3c2n(c(c3CCCOc4cccc5c4cccc5)C(=O)O)CCN6CCOCC6

InChI Key InChIKey=ZFODCXXHTZVRJL-UHFFFAOYSA-N

Data  5 KI

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50078154   

LigandPNGBDBM50078154(CHEMBL3417694)
Affinity DataKi:  9nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50078154(CHEMBL3417694)
Affinity DataKi:  21nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50078154(CHEMBL3417694)
Affinity DataKi:  190nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details PDB3D3D Structure (crystal)
TargetAlbumin(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50078154(CHEMBL3417694)
Affinity DataKi:  360nMAssay Description:Displacement of probe S1 from recombinant human serum albumin domain 3 after 5 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMed
LigandPNGBDBM50078154(CHEMBL3417694)
Affinity DataKi:  470nMAssay Description:Displacement of fluorescent labeled NOXA peptide from recombinant human MCL1 by fluorescence polarization assay in presence of 1% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50078154(CHEMBL3417694)
Affinity DataKi:  1.23E+3nMAssay Description:Displacement of F-Bak (GQVGRQLAIIGDK(6-FAM)INR-amide) from MCL1 (unknown origin) after 1 hr by TR-FRET assay in presence of 10% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/26/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)