BDBM50096463 CHEMBL70176::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide::N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)-3-methylbenzamide

SMILES Cc1cccc(c1N(Cc2cccnc2)S(=O)(=O)c3ccc(cc3)OC)C(=O)NO

InChI Key InChIKey=AINJYWXKBKRQSX-UHFFFAOYSA-N

Data  24 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50096463   

TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 18nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 5nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of Matrix metalloprotease-13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of Matrix metalloprotease-13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 329nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 391nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 645nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 356nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 329nMAssay Description:In vitro inhibition of Matrix metalloprotease-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 356nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 7nMAssay Description:In vitro inhibition of Matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 143nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 143nMAssay Description:Inhibitory activity against Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 8nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMatrix metalloproteinase-9(Human)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 5nMAssay Description:In vitro ability to inhibit matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 231nMAssay Description:In vitro inhibition of TNF-alpha converting enzyme (TACE)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50096463(N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 143nMAssay Description:In vitro inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed