BDBM50115394 CHEMBL3608461

SMILES OC[C@@H](N1CCCn2cc(cc2C1=O)-c1ccnc(N[C@H]2CC[C@@H](O)C2)n1)c1cccc(Cl)c1

InChI Key InChIKey=ZQJZOIMPHMQLOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50115394   

TargetMitogen-activated protein kinase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50115394(CHEMBL3608461)
Affinity DataIC50: 0.190nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50115394(CHEMBL3608461)
Affinity DataIC50: 52nMAssay Description:Inhibition of ERK2 in human A375 cells assessed as phosphorylated FRA levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2016
Entry Details Article
PubMed