BDBM50117744 CHEMBL3613789

SMILES CC1(CN=C(S1)N2CCN(CC2)c3c4cc(sc4ncn3)CC(F)F)C

InChI Key InChIKey=CCXCUJOBJWILJV-UHFFFAOYSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50117744   

TargetMenin(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50117744(CHEMBL3613789)
Affinity DataIC50: 65nMAssay Description:Inhibition of N-terminal thioredoxin His6-tagged full-length human menin expressed in Escherichia coli Rosetta (DE3) cells assessed as reduction in m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)