BDBM50118630 CHEMBL3617090

SMILES c1ccc(cc1)CC2=CC(=O)n3c(c(cn3)C#N)N2

InChI Key InChIKey=RAGSEECOXCGMEQ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50118630   

LigandPNGBDBM50118630(CHEMBL3617090)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human cloned BCATm expressed in Escherichia coli BL21 DE3 assessed as L-glutamate production from alpha-ketoglutarate after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50118630(CHEMBL3617090)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human BCATm incubated for 10 mins by Amplex red- based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)