BDBM50124203 5-IODOURACIL::5-Iodo-1H-pyrimidine-2,4-dione::CHEMBL1173

SMILES C1=C(C(=O)NC(=O)N1)I

InChI Key InChIKey=KSNXJLQDQOIRIP-UHFFFAOYSA-N

Data  1 IC50

PDB links: 4 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50124203   

TargetDihydropyrimidine dehydrogenase [NADP(+)](Human)
Nippon Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50124203(5-Iodo-1H-pyrimidine-2,4-dione | 5-IODOURACIL | CH...)
Affinity DataIC50: 220nMAssay Description:Inhibitory activity against dihydropyrimidine dehydrogenase (DPD)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)