BDBM50127302 2-Chloro-5-(3-chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-nicotinonitrile::CHEMBL288046

SMILES Cn1cncc1[C@@H](c2ccc(cc2)C#N)OCc3c(cc(c(n3)Cl)C#N)c4cccc(c4)Cl

InChI Key InChIKey=JVWHVGIRXILXMU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127302   

TargetGeranylgeranyl transferase type-1 subunit beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127302(2-Chloro-5-(3-chloro-phenyl)-6-[(4-cyano-phenyl)-(...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50127302(2-Chloro-5-(3-chloro-phenyl)-6-[(4-cyano-phenyl)-(...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed