BDBM50129817 CHEMBL3628685

SMILES COc1ccc(CNC(=O)c2ccc(OC(F)F)c(OC3CCCC3)c2)cc1

InChI Key InChIKey=DBNDIIUELFNMBG-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50129817   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 94nMAssay Description:Inhibition of human full-length PDE4D7 using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Qingdao University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 976nMAssay Description:Inhibition of human recombinant PDE4B1 using FAM-cGMP as substrate preincubated with compound for 15 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Qingdao University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 976nMAssay Description:Inhibition of human full-length PDE4B1 using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of core catalytic domains of human PDE4 using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE11A using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE10A2 using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE1A using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE2A using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE5A using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE3B using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE7A using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE6C using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE9A2 using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
LigandPNGBDBM50129817(CHEMBL3628685)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human PDE8A1 using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed