BDBM50138665 6-Carbamimidoyl-naphthalene-2-carboxylic acid (1-isopropyl-1,2,3,4-tetrahydro-isoquinolin-7-yl)-amide::6-carbamimidoyl-N-(1-isopropyl-1,2,3,4-tetrahydroisoquinolin-7-yl)-2-naphthamide::CHEMBL442201

SMILES CC(C)[C@H]1c2cc(ccc2CCN1)NC(=O)c3ccc4cc(ccc4c3)C(=N)N

InChI Key InChIKey=DARQQJKHXPXSRO-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50138665   

TargetUrokinase-type plasminogen activator(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138665(6-carbamimidoyl-N-(1-isopropyl-1,2,3,4-tetrahydroi...)
Affinity DataKi:  23.5nMAssay Description:Binding affinity to human urokinase-type plasminogen activator (microPa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138665(6-carbamimidoyl-N-(1-isopropyl-1,2,3,4-tetrahydroi...)
Affinity DataKi:  25nMAssay Description:Inhibition of urokinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138665(6-carbamimidoyl-N-(1-isopropyl-1,2,3,4-tetrahydroi...)
Affinity DataKi:  43nMAssay Description:Binding affinity against porcine trypsin was determined.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138665(6-carbamimidoyl-N-(1-isopropyl-1,2,3,4-tetrahydroi...)
Affinity DataKi:  230nMAssay Description:Binding affinity against human plasma kallikrein.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138665(6-carbamimidoyl-N-(1-isopropyl-1,2,3,4-tetrahydroi...)
Affinity DataKi:  631nMAssay Description:Binding affinity towards human plasmin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138665(6-carbamimidoyl-N-(1-isopropyl-1,2,3,4-tetrahydroi...)
Affinity DataKi:  1.12E+3nMAssay Description:Binding affinity towards human Tissue type plasminogen activator.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50138665(6-carbamimidoyl-N-(1-isopropyl-1,2,3,4-tetrahydroi...)
Affinity DataKi:  5.72E+3nMAssay Description:Binding affinity against human alpha thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed