BDBM50150069 CHEMBL3774931

SMILES CCCCc1c(nc2nc(nn2c1C)SCc3nc4c(n3CC)C(=O)NC(=O)N4CCCC)C

InChI Key InChIKey=FTDVJTZJKKOHSY-UHFFFAOYSA-N

Data  5 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50150069   

TargetBromodomain-containing protein 4(Human)
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150069(CHEMBL3774931)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity to his-tagged human BRD4 bromodomain1 by isothermal titration calorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 3(Human)
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150069(CHEMBL3774931)
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of GST-tagged human BRD3 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2017
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150069(CHEMBL3774931)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of GST-tagged human BRD2 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2017
Entry Details Article
PubMed
TargetBromodomain testis-specific protein(Human)
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150069(CHEMBL3774931)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GST-tagged human BRDT bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2017
Entry Details Article
PubMed
TargetATPase family AAA domain-containing protein 2(Human)
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150069(CHEMBL3774931)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GST-tagged human ATAD2 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2017
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Centre National de la Recherche Scientifique/INSERM/ULP

Curated by ChEMBL
LigandPNGBDBM50150069(CHEMBL3774931)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of GST-tagged human BRD4 bromodomain1 using H4KAc 5/8/12/16 peptide as substrate incubated overnight by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)