BDBM50168052 (4-Iodo-phenyl)-thiocarbamic acid 2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethyl ester::CHEMBL191910::O-2-(1,3-dioxoisoindolin-2-yl)ethyl4-iodophenylcarbamothioate::O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] (4-iodophenyl)thiocarbamate

SMILES c1ccc2c(c1)C(=O)N(C2=O)CCOC(=S)Nc3ccc(cc3)I

InChI Key InChIKey=CYYIBMGIJWXZEP-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50168052   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50168052(O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103R)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50168052(O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl...)
Affinity DataIC50: 90nMAssay Description:Inhibitory concentration against HIV-1 wild type reverse transcriptase (IIIB)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50168052(O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (Y181C)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50168052(O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against HIV-1 mutant reverse transcriptase (K103N+Y181C)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)