BDBM50172116 CHEMBL3809983

SMILES Cc1ccc(cc1N(c2cn(c3c2cccc3)C(=O)C)C(=O)c4cccc(c4)C(F)(F)F)O

InChI Key InChIKey=GRQZQCNAGDASPY-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50172116   

TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50172116(CHEMBL3809983)
Affinity DataKd:  3.90E+4nMAssay Description:Competitive binding affinity to human His-tagged BRAZ2B (1858 to 1972 residues) expressed in T7 phage-infected Escherichia coli BL21(DE3) cells measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Z£Rich

Curated by ChEMBL
LigandPNGBDBM50172116(CHEMBL3809983)
Affinity DataIC50: 2.70E+4nMAssay Description:Competitive binding affinity to His-tagged BRAZ2B (unknown origin) expressed in Escherichia coli BL21(DE3) cells by AlphaScreen assay in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)