BDBM50174389 1-(2-Chloro-4-fluoro-benzoyl)-3-(5-hydroxy-2-methoxy-phenyl)-urea::CHEMBL198408::N-(2-CHLORO-4-FLUOROBENZOYL)-N'-(5-HYDROXY-2-METHOXYPHENYL)UREA

SMILES COc1ccc(cc1NC(=O)NC(=O)c2ccc(cc2Cl)F)O

InChI Key InChIKey=RFOBTYLRURSVJE-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50174389   

TargetGlycogen phosphorylase, liver form(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50174389(1-(2-Chloro-4-fluoro-benzoyl)-3-(5-hydroxy-2-metho...)
Affinity DataIC50: 23nMpH: 7.2Assay Description:Inhibitory concentration against human liver glycogen phosphorylase enzyme by the addition of glucose-1-phosphate upon incubating for 40 min at 25 de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlycogen phosphorylase, liver form(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50174389(1-(2-Chloro-4-fluoro-benzoyl)-3-(5-hydroxy-2-metho...)
Affinity DataIC50: 22.9nMpH: 7.2Assay Description:Logarithmic inhibitory concentration against human liver glycogen phosphorylase enzyme by the addition of glucose-1-phosphate and incubated for 40 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)