BDBM50179236 2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxazol-6-yloxy)propoxy)-1H-indol-1-yl)acetic acid::2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID::CHEMBL200495

SMILES CCCc1c(ccc2c1onc2C(F)(F)F)OCCCOc3ccc4c(c3)ccn4CC(=O)O

InChI Key InChIKey=TWVYNPULGKGJOS-UHFFFAOYSA-N

Data  7 IC50  3 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50179236   

TargetPeroxisome proliferator-activated receptor gamma(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179236(2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50: 152nMAssay Description:Displacement of [3H]rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179236(2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50: 96nMAssay Description:Displacement of [3H]L-783483 from human PPAR delta by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179236(2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50: 496nMAssay Description:Displacement of [3H]L-783483 from human PPAR alpha by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179236(2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataEC50:  14nMAssay Description:Functional activity at human PPAR alpha in Huh7 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179236(2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50: 152nMAssay Description:Displacement of [3H]rosiglitazone from human PPAR gamma by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179236(2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataEC50:  230nMAssay Description:Functional activity at human PPAR gamma in Huh7 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179236(2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataEC50:  10nMAssay Description:Functional activity at human PPAR delta in Huh7 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179236(2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50: 95.9nMAssay Description:Agonist activity at PPARdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179236(2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50: 152nMAssay Description:Agonist activity at PPARgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50179236(2-(5-(3-(7-propyl-3-(trifluoromethyl)benzo[d]isoxa...)
Affinity DataIC50: 495nMAssay Description:Agonist activity at PPARalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed