BDBM50185006 CHEMBL3823505

SMILES c1cncc2c1cc3c(c2)cnc(n3)N

InChI Key InChIKey=HTMYPIWEXZOFDM-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50185006   

TargetCyclin-dependent kinase 5 activator 1(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50185006(CHEMBL3823505)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GST-tagged human recombinant CDK5/p25 expressed in Escherichia coli using histone H1 as substrate incubated for 30 mins in presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50185006(CHEMBL3823505)
Affinity DataIC50: 190nMAssay Description:Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Clermont Auvergne

Curated by ChEMBL
LigandPNGBDBM50185006(CHEMBL3823505)
Affinity DataIC50: 180nMAssay Description:Inhibition of GST-tagged rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMed
TargetCasein kinase I delta/epsilon(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50185006(CHEMBL3823505)
Affinity DataIC50: 800nMAssay Description:Inhibition of CK1delta/epsilon (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Louisiana At Lafayette

Curated by ChEMBL
LigandPNGBDBM50185006(CHEMBL3823505)
Affinity DataIC50: 180nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed