BDBM50190111 CHEMBL327844

SMILES c1ccc(cc1)CC[C@@H](N)[P@@](=O)(C[C@@H](Cc2ccccc2)C(=O)O)O

InChI Key InChIKey=QELOIXSGJMIHBZ-UHFFFAOYSA-N

Data  5 KI

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50190111   

TargetM17 leucyl aminopeptidase(Plasmodium falciparum (isolate 3D7))
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190111(CHEMBL327844)
Affinity DataKi:  13nMAssay Description:Inhibition of Plasmodium falciparum LAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytosol aminopeptidase(Pig)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190111(CHEMBL327844)
Affinity DataKi:  66nMAssay Description:Inhibition of porcine LAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190111(CHEMBL327844)
Affinity DataKi:  276nMAssay Description:Inhibition of porcine APNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190111(CHEMBL327844)
Affinity DataKi:  350nMAssay Description:Inhibition of human ERAP2 preincubated for 30 to 60 mins followed by addition of Arg-AMC as substrate measured for 15 mins by spectrofluorimetric met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Wroclaw University of Technology

Curated by ChEMBL
LigandPNGBDBM50190111(CHEMBL327844)
Affinity DataKi:  1.91E+4nMAssay Description:Inhibition of recombinant human ERAP1 using L-AMC as substrate measured for 15 to 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2017
Entry Details Article
PubMed