BDBM50195788 CHEMBL3961799

SMILES CC(C)CN([C@H]1CCCNC1)C(=O)c2cnc(nc2NCc3ccco3)C(C)(C)C

InChI Key InChIKey=RRLGPXVRIYOXIU-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50195788   

TargetRenin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50195788(CHEMBL3961799)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of renin in human plasma by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50195788(CHEMBL3961799)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of recombinant human preprorenin expressed in human 293F cells using angiotensinogen as substrate preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)