BDBM50199714 CHEMBL3922564

SMILES CCN1C(=O)C(=C(C(=N1)c2ccccc2)C(=O)C)Nc3ccc(cc3)C(=O)O

InChI Key InChIKey=HAISKEJFQSPYKC-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50199714   

TargetAcetylcholinesterase(Electric eel)
Henan University

Curated by ChEMBL
LigandPNGBDBM50199714(CHEMBL3922564)
Affinity DataIC50: 60nMAssay Description:Inhibition of electric eel AChE using ATC as substrate preincubated for 15 mins followed by substrate addition by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2018
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Henan University

Curated by ChEMBL
LigandPNGBDBM50199714(CHEMBL3922564)
Affinity DataIC50: 46nMAssay Description:Inhibition of horse serum BChE using BTC as substrate preincubated for 15 mins followed by substrate addition by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50199714(CHEMBL3922564)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human recombinant PDE4B1 assessed as reduction in [3H]cAMP hydrolysis to [3H]AMP incubated for 60 mins by PDE-SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)