BDBM50232876 CHEMBL4094048

SMILES CC(=O)Nc1ccc(c(c1)Cl)OC

InChI Key InChIKey=WNOVNNUWOUKIOL-UHFFFAOYSA-N

Data  2 Kd

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232876   

TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50232876(CHEMBL4094048)
Affinity DataKd:  2.80E+6nMAssay Description:Binding affinity to human N-terminal His6-tagged truncated PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD-3-phosphoglycerate dehydrogenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50232876(CHEMBL4094048)
Affinity DataKd:  1.30E+6nMAssay Description:Binding affinity to human PHGDH (3 to 314 residues) expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)