BDBM50234160 CHEMBL4063902

SMILES Cn1c(nc(n1)c2cnc(c(n2)n3ccc(n3)C(=O)N)N)C4(CC4)c5ccccc5

InChI Key InChIKey=PPNTYGOEVAXAOA-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234160   

LigandPNGBDBM50234160(CHEMBL4063902)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of recombinant human His6-tagged PI3Kgamma (144 to 1102 residues) using DiC8-PIP2 as substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2019
Entry Details Article
PubMed
LigandPNGBDBM50234160(CHEMBL4063902)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110alpha/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2019
Entry Details Article
PubMed
LigandPNGBDBM50234160(CHEMBL4063902)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110beta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2019
Entry Details Article
PubMed
LigandPNGBDBM50234160(CHEMBL4063902)
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)