BDBM50234165 CHEMBL4090281

SMILES C[C@@H](c1nc(nn1C)c2cnc(c(n2)n3c4ccccc4nn3)N)N5CCOCC5

InChI Key InChIKey=FXHVFSHZRDKMCE-UHFFFAOYSA-N

Data  4 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234165   

LigandPNGBDBM50234165(CHEMBL4090281)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110alpha/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2019
Entry Details Article
PubMed
LigandPNGBDBM50234165(CHEMBL4090281)
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110delta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50234165(CHEMBL4090281)
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of recombinant human His6-tagged PI3Kgamma (144 to 1102 residues) using DiC8-PIP2 as substrate preincubated for 15 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50234165(CHEMBL4090281)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of recombinant human His6-tagged PI3K p110beta/p85alpha using DiC8-PIP2 as substrate preincubated for 15 mins followed by substrate additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2019
Entry Details Article
PubMed