BDBM50234316 CHEMBL2391621

SMILES COC(=O)c1c[nH]c2c1cccn2

InChI Key InChIKey=XYRUNIAHPKBUJT-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234316   

TargetTyrosine-protein kinase receptor UFO(Human)
Oribase Pharma

Curated by ChEMBL

LigandBDBM50234316(CHEMBL2391621)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human His-tagged AXL expressed in insect cells after 60 mins by Z'-LYTE assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
6/14/2019
Entry Details Article
Copy Entry DOIPubMed
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Sanofi

Curated by ChEMBL

LigandBDBM50234316(CHEMBL2391621)Copy SMILESCopy InChI

Affinity DataIC50: 3.94E+4nMAssay Description:Inhibition of MEK1 (unknown origin) using ATP and ERK2 K54R as substrate after 60 to 80 mins by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
9/1/2020
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL