BDBM50237194 CHEMBL4091108

SMILES c1ccc(cc1)C(c2ccccc2)N3CCN(CC3)CC(=O)Nc4ccc(cc4)S(=O)(=O)N

InChI Key InChIKey=MZCJQCUNQFZSCL-UHFFFAOYSA-N

Data  4 KI

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50237194   

TargetCarbonic anhydrase 7(Human)
University of Delhi

Curated by ChEMBL
LigandPNGBDBM50237194(CHEMBL4091108)
Affinity DataKi:  8.90nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
University of Delhi

Curated by ChEMBL
LigandPNGBDBM50237194(CHEMBL4091108)
Affinity DataKi:  43nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
University of Delhi

Curated by ChEMBL
LigandPNGBDBM50237194(CHEMBL4091108)
Affinity DataKi:  1.77E+3nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2019
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Delhi

Curated by ChEMBL
LigandPNGBDBM50237194(CHEMBL4091108)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 12 incubated for 15 mins prior to testing by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/5/2019
Entry Details Article
PubMed