BDBM50239501 CHEMBL4093989

SMILES CC(C)Oc1ccccc1C(=O)N

InChI Key InChIKey=BTHLVVULQLRTBK-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239501   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50239501(CHEMBL4093989)Copy SMILESCopy InChI

Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of N-terminal His6-tagged human full length IRAK4 preincubated for 20 mins followed by biotinylated-AGAGRDKYKTLRQIR substrate addition in ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
9/22/2019
Entry Details Article
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL

TargetInterleukin-1 receptor-associated kinase 4(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50239501(CHEMBL4093989)Copy SMILESCopy InChI

Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of full-length IRAK4 (unknown origin) in presence of ATP by DELFIA assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidPDBSimilars

In Depth
Date in BDB:
12/16/2024
Entry Details
Copy Entry DOIPubMedPDB3D Structure (crystal)
Copy Rxn URL